Grape or Grain but Never the Twain? A Randomized Controlled Multiarm Matched-Triplet Crossover Trial of Beer and Wine

Hangovers!  The horrible consequences of over indulging alcoholic beverages.  Chronic drinking can cause increased health risks along with driving impairment, reduced productivity, poor academic performance, and workplace absenteeism.

There are some folk wisdom sayings about alcohol that a recent study out of Germany decided to test the validity of.

“Beer before wine and you’ll feel fine; wine before beer and you’ll feel queer”

Can the order or the mix of alcoholic drinks have an affect on a hangover?

Subjects were chosen by age, gender, body composition, alcohol drinking habits and hangover frequency.  They were then divided into 4 groups.  There would be two days of testing 1 week apart.  The participants self-rated their own hangovers after each session.

  • Group 1 Day 1 Consumed Beer and then Wine
  • Group 2 Day 1 Consumed Wine and then Beer
  • Control Group 1 Day 1 Beer Only
  • Control Group 2 Day 1 Wine Only

1 Week Later

  • Group 1 Day 2 flip flopped and Drank Wine then Beer
  • Group 2 Day 2 flip flopped and Drank Beer than Wine
  • Control Group 1 Day 2 drank Wine Only
  • Control Group 2 Day 2 Beer Only

Results showed neither type of alcohol nor the order in which the study participants drank and any significant effect on hangover intensity.

Women tended to have worse hangovers than men.  And interestingly, those who only drank wine or beer had worse hangovers than those who mixed the two.

According to webmd there are 12 Health Risks of Chronic Heavy Drinking.

  • Anemia
  • Cancer
  • Cardiovascular disease
  • Cirrhosis (alcohol is toxic to liver cells)
  • Dementia – heavy drinking speeds brain shrinkage
  • Depression
  • Seizures
  • Gout – formation of uric acid crystals in the joints
  • High blood pressure
  • Infectious disease – heavy drinking harms your immune system
  • Nerve damage – alcoholic neuropathy
  • Pancreatitis – 60% caused from alcohol consumption

Check out the HealthStatus Blood Alcohol Calculator HERE!

Alcohol Facts

  • 1Drinking alcohol is linked to car crashes, falls, occupational injuries, domestic violence, drowning, suicide and homicide.
  • 2Heavy drinking is consuming 8 drinks or more for women and 15 drinks or more for men.
  • 3Alcohol consumption is associated with violent crime.

“Alcohol does all kinds of things in the body, and we’re not fully aware of all its effects,” says James C. Garbutt, MD, professor of psychiatry at the University of North Carolina at Chapel Hill School of Medicine and a researcher at the university’s Bowles Center for Alcohol Studies. “It’s a pretty complicated little molecule.”

Sources:
https://academic.oup.com/ajcn/article/109/2/345/5307130
https://www.webmd.com/mental-health/addiction/features/12-health-risks-of-chronic-heavy-drinking#1
https://www.medicalnewstoday.com/articles/297734.php

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Written by HealthStatus
Medical Writer & Editor

HealthStatus has been operating since 1998 providing the best interactive health tools on the Internet, millions of visitors have used our health risk assessment, body fat and calories burned calculators. The HealthStatus editorial team has continued that commitment to excellence by providing our visitors with easy to understand high quality health content for many years.

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