Antidepressants Do Work, Some Better Than Others: Study

Good news just when you might be feeling down; antidepressant medication does work. A review of previously conducted medical research studies confirms it. Over five hundred studies, comprising more than a hundred thousand patients, was examined to confirm their results. Every study participant was taking one or more antidepressants.

The review found that antidepressant drugs seem to work to a moderate effect in the short term. An ongoing concern remains full understanding of how such medications can help over the long term. Not as many studies have looked into the effectiveness of antidepressants over longer periods of time. The review study’s researchers say they do help to improve patient condition, but just how much is difficult to quantify.

Another finding was that there seemed to be no clear winner among the various medications that were examined. They all worked similarly, and produced similar results. Which is good and bad news. Good, in that there’s not a magic pill that is the one best answer; but bad for the same reason. The main takeaway from the similarities in how well they work to improve a patient’s mental condition is to focus on the side effects. That’s where the medications did differ, so doctors and patients should seek to find the right medications that carry the fewest unwanted physical effects for each particular patient.

Key Points:

  • 1There are several antidepresents on the market, and they do not help people the same way.
  • 2Antidepressants and therapy, go hand in hand when battling depression.
  • 3Lexapro and Trintellix, have been found to be most effective, however they are not one stop shop solution for depression.


What works well for one person doesn’t always work well for another, so there may be some trial and error involved in finding the right medication for you.
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Written by HealthStatus
Medical Writer & Editor

HealthStatus has been operating since 1998 providing the best interactive health tools on the Internet, millions of visitors have used our health risk assessment, body fat and calories burned calculators. The HealthStatus editorial team has continued that commitment to excellence by providing our visitors with easy to understand high quality health content for many years.

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